A. Ganem-Quintanar, D. Quintanar-Guerrero, P. Buri
Jan 1, 2000
Citations
1
Influential Citations
180
Citations
Quality indicators
Journal
Drug Development and Industrial Pharmacy
Abstract
Although monoolein is a well-known molecule commonly used as an emulsifying agent and as a food additive since the 1950s, its potential applicability in the pharmaceutical industry has not been considered in great detail. Recently, there has been a flurry of activity concerned with the possibility of using monoolein as a material for different pharmaceutical applications. The explosion of interest in this field is evidenced by an increase in the number of publications in the area (1). Figure 1 shows the percentage of consulted references of monoolein versus publication year. It is important to point out that only articles falling in the pharmaceutical area were considered when creating this graphic. Between 1978 and 1987, monoolein was used mainly as an absorption enhancer in combination with bile salts and as an emulsifier. It was in 1984 that monoolein was first