D. Ashok, A. Ganesh, B. Lakshmi
Oct 21, 2015
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Influential Citations
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Quality indicators
Journal
Russian Journal of General Chemistry
Abstract
A novel series of 2-(2-ethoxyindol-3-ylidene)-1-arylethanones and 2-(5-bromo-2-ethoxyindol-3-ylidene)-1-arylethanones were synthesized from 1H-indole-2,3-dione or 5-bromo-1H-indole-2,3-dione, arylmethylketone and ethyl alcohol in the presence of sulphuric acid (conc.) under microwave and ultrasound irradiation. All newly synthesized compounds were characterized by elemental analysis and spectral methods: IR, 1H and 13C NMR, mass spectra. Evaluation of the in vitro antibacterial activity against bacterial (Grampositive Staphylococcus aureus and Gram-negative Escherichia coli) and fungal (Aspergillus niger and Candida metapsilosis) strains revealed high antimicrobial activity of some tested compounds.