Paper

Multi-dose oral abuse deterrent formulation of Loperamide using Hot melt extrusion.

Published Oct 5, 2019 · Yige Fu, S. Palekar, P. Nukala

International journal of pharmaceutics

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Abstract

Abstract hidden due to publisher request; this does not indicate any issues with the research. Click the full text link above to read the abstract and view the original source.

Study Snapshot

The developed tablet technology effectively deters multi-dose oral abuse of loperamide by allowing immediate release for diarrheic patients but stopping drug release in intentional multi-dose ingestion.

PopulationOlder adults (50-71 years)

Sample size24

MethodsObservational

OutcomesBody Mass Index projections

ResultsSocial networks mitigate obesity in older groups.

Multi-dose oral abuse deterrent formulation of Loperamide using Hot melt extrusion.

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