Xiao Geng, Xia Wu, Can Wang
Nov 8, 2018
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0
Influential Citations
9
Citations
Journal
Chemical communications
Abstract
An efficient method for constructing 2-acyl-3-aminoindoles from methyl ketones and 2-aminobenzonitriles is described, in which NaHS·nH2O is used as a novel umpolung reagent for the first time in organic synthesis. Mechanistic studies revealed that the key step involved an Eschenmoser sulfide contraction reaction.