S. Kotha, Kuldeep Singh
Dec 20, 2004
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Influential Citations
26
Citations
Journal
Tetrahedron Letters
Abstract
An efficient method for N-alkylation of diethyl acetamidomalonate (DEAM) is reported. C-Alkenylation was achieved by treating the N-alkenylated DEAM with various electrophiles in the presence of Cs2CO3. RCM reactions of C- and N-alkenylated products gave cyclic amino acid derivatives in good yields.