T. Baburaj, S. Thambidurai
May 2, 2012
Citations
0
Influential Citations
8
Citations
Journal
Tetrahedron Letters
Abstract
Terminal tert-butyloxycarbonyl (Boc) protected hydrazino acids, useful intermediates for modified peptides and biologically active heterocyclic derivatives, were synthesized by electrophilic amination methodology using N-Boc-O-tosyl hydroxylamine as an efficient NH-Boc transfer reagent. Also, we have demonstrated the conversion of other amino acid derivatives such as amino esters and amino alcohols into β-Boc-hydrazino derivatives using this reagent.