J. Hynes, W. Doubleday, A. Dyckman
Jan 17, 2004
Citations
0
Influential Citations
63
Citations
Journal
The Journal of organic chemistry
Abstract
A survey of several electrophilic ammonia reagents for the N-amination of indole- and pyrrole-containing heterocycles revealed that monochloramine (NH(2)Cl) is an excellent reagent for this transformation. Pyrroles and indoles containing a variety of substitution were aminated on nitrogen with isolated yields ranging from 45% to 97%.