M. Babaie, H. Sheibani
Apr 1, 2011
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Journal
Arabian Journal of Chemistry
Abstract
Abstract A four-component reaction of hydrazine hydrate or phenyl hydrazine, ethyl 3-alkyl-3-oxo propanoate, aldehydes and malononitrile has been achieved in the presence of nanosized magnesium oxide as a highly effective heterogeneous base catalyst to produce of 6-amino-3-alkyl-4-aryl-5-cyano-1,4-dihydropyrano[2,3- c ]pyrazole derivatives in excellent yields and in a short experimental time. This method is simple and rapid for focusing a pyrano ring with a pyrazole ring.