M. Leanna, H. Morton
Jul 9, 1993
Citations
0
Influential Citations
34
Citations
Journal
Tetrahedron Letters
Abstract
Abstract N(Boc)-L-(2-Bromoallyl)-glycine ( 1 ) was synthesized from diethylacetamidomalonate and 2,3-dibromopropene in a one-pot procedure (75 % overall yield). The enantiomers were efficiently separated via a tandem biocatalytic kinetic hydrolytic resolution. 1 was elaborated to several other interesting unnatural amino acid.