G. Dmitrienko, K. E. Nielsen, C. Steingart
1990
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron Letters
Abstract
Abstract N-Cyano-2,3-dialkylindoles, available by reaction of N-sodioindoles with phenyl cyanate, are substantially less reactive than N-acylindoles under electrophilic bromination conditions but readily yield sidechain brominated products under free radical conditions. Ceric ammonium nitrate oxidation of N-cyano-4,7-dimethoxy-2,3-disubstituted indoles yields the corresponding N-cyanoindole-4,7-diones which are potentially synthons for construction of kinamycins, 1.