R. Charles, E. Gil-av
Jul 25, 1980
Citations
0
Influential Citations
22
Citations
Journal
Journal of Chromatography A
Abstract
Abstract The synthesis and chromatographic properties of N-docosanoyl- l -valine-2-(2-methyl)- n -heptadecylamide are described. It has been employed as a stationary phase at column temperatures up to 200°C and it shows excellent stereoselectivity for various classes of compounds, including, in particular, N-trifluoroacetyl (N-TFA) esters of α- and γ-amino acids, aromatic N-TFA amines, N-TFA-O-acyl amino alcohols and N-TFA-α-methylvaline isopropyl ester. The influence of lengthening the chains of R′ and R‴ on the properties of the diamides R′CONHCH(R″)CONHR‴ is discussed.