S. Xiaodong, Cheng-cheng Feng, S. Xin
2010
Citations
0
Influential Citations
1
Citations
Quality indicators
Journal
The Chinese Journal of Dermatovenereology
Abstract
Objective To investigate the clinical features of neurosyphilis presenting as diplopia.Methods Case reports were identified from Medline,Embase and CBM.Case reports of diplopia attributed to neurosyphilis were enrolled.Two reviewers independently assessed studies quality and extracted date.The Excel 2007 software was used for statistical analysis.Results Twelve studies involving 12 patients were evaluated.The clinical feature of neurosyphilis presenting as diplopia included:more often in man,diplopia being key symptom,changes in cerebrospinal fluid,no specific neuroimaging,good response to penicillin,and good prognosis.Conclusion Diplopia as one of the prominent symptom can be found in diverse types of neurosyphilis,which diagnosis is often delayed.More attention should be paid to the neurosyphilis diagnosis of patients with diplopia.Penicillin remains the mainstay of treatment for neurosyphilis.