N. Washington, C. Washington, Clive G. Wilson
Apr 1, 1986
Citations
0
Influential Citations
3
Citations
Quality indicators
Journal
International Journal of Pharmaceutics
Abstract
Abstract The in vitro neutralization properties of magnesium trisilicate mixture BP and its ingredients have been examined using the Rossett and Rice test. It is concluded that the inclusion of the principal component, magnesium trisilicate, in the mixture is unwarranted due to the failure to demonstrate a significant neutralizing action. This appears to be due to the extremely slow rate of reaction of this compound with hydrochloric acid.