J. Krantz, D. V. Kibler, F. K. Bell
Nov 1, 1944
Citations
0
Influential Citations
14
Citations
Journal
Journal of Pharmacology and Experimental Therapeutics
Abstract
1. A new compound, the basic aluminum salt of aminoacetic acid, has been prepared. 2. Its capacity to buffer and neutralize hydrochloric acid has been studied. Its prompt and prolonged buffering of acid, bespeaks the use of the compound in the treatment of hyperacidity and peptic ulcer. On the basis of the aluminum content, basic aluminum aminoacetate is 42 per cent more efficient in acid-consuming power than dried aluminum hydroxide gel. 3. Certain theoretical considerations of its use have been discussed. 4. Feeding studies on rats and preliminary clinical trials as an antacid in man are recorded.