A. Dwek, P. W. Kent, A. V. Xavier
Nov 1, 1971
Citations
0
Influential Citations
18
Citations
Journal
European journal of biochemistry
Abstract
1 The synthesis and nuclear-magnetic-resonance spectra of N-fluoroacetyl-d-glucosamine are described, together with 19F chemical shifts for some monosaccharides substituted with fluorine at different positions. 2 The sugar derivative N-fluoroacetyl-d-glucosamine is inhibitory towards lysozyme, 50% of full inhibition being given by about 15 mM. 3 At pH 5.4, addition of this sugar derivative to lysozyme solutions results in a concentration-dependent broadening and down-field shift in the 19F-resonance, of both anomeric forms. The α-anomeric form is shifted more than the β-form.