Yadong Pang, Guoduan Liang, Fukai Xie
Feb 20, 2019
Citations
0
Influential Citations
16
Citations
Journal
Organic & biomolecular chemistry
Abstract
N-Fluorobenzenesulfonimide (NFSI) was identified for the first time as a highly effective Ag(i)-catalyst attenuator in the annulation of a tryptamine-derived ynesulfonamide to azepino[4,5-b]indole derivatives. Substrate tolerances were examined thoroughly and a plausible mechanism was proposed. The interaction between the Ag(i) catalyst and NFSI was probed by density functional theory (DFT) calculations. This study provided a highly efficient method to synthesize azepino[4,5-b]indole derivatives.