W. Ying, D. Desmarteau, Y. Gotoh
1996
Citations
0
Influential Citations
51
Citations
Journal
Tetrahedron
Abstract
Abstract Direct fluorination of imines with N -fluoro-bis[(trifluoromethyl)sulfonyl]imide 1 afforded mono and/or difluoroketones without the need of a strong base to first generate the imine anions. Structurally related 2- and 4- methyl-substituted pyridines gave the respective fluoromethyl pyridines with 1 . Our results suggest that an enamine intermediate plays a key role in these reactions.