Pengrui Jiang, Jing-Yu Guo, Minghua Gong
May 20, 2021
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Organic & biomolecular chemistry
Abstract
N-Heterocyclic carbene-catalyzed [3 + 3] annulation of bromoenals with 2-aminochromones has been successfully developed. A structurally diverse set of chromeno[2,3-b]pyridinones was efficiently constructed in acceptable to excellent yields. The reaction features mild reaction conditions, a broad substrate scope, and easy scale-up.