A. Katoh, J. Ohkanda, Y. Itoh
Oct 5, 1992
Citations
0
Influential Citations
5
Citations
Journal
Chemistry Letters
Abstract
N-Hydroxyamide-containing heterocycles, 1-hydroxy-4,6-dimethyl-2(1H)-pyrimidinone and -5,6-dimethyl-2(1H)-pyrazinone, are prepared. Judging from the result of model dipeptide (Z-Ala-Phe-OMe) formation, these compounds are found to be new effective additives for peptide synthesis by the dicyclohexylcarbodiimide (DCC) method at the points of high yield and no detectable racemization.