Sheng Xu, Kuai Wang, Wangqing Kong
Sep 3, 2019
Citations
0
Influential Citations
29
Citations
Journal
Organic letters
Abstract
An easy-to-handle Ni-catalyzed three-component reductive arylacylation of alkenes using isobutyl chloroformate as a CO source was described. This reaction operates under mild reaction conditions without the need to use toxic CO gas or metal carbonyl reagents. In addition, this method allows for rapid synthesis of 3,3-disubstituted oxindoles with an all-carbon quaternary stereocenter containing a ketone group in good yields with broad substrate scope.