S. Djurdjevic, James R. Green
Oct 14, 2013
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0
Influential Citations
10
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Journal
Organic letters
Abstract
Hexacarbonyldicobalt complexes of biaryl-substituted 4-methoxybutynones and 4-methoxy-2-butynes undergo intramolecular Nicholas reactions to form dibenzocyclooctyne-Co2(CO)6 complexes in good yields. Reductive decomplexation of the cyclization products is possible, and the method has been applied to a formal synthesis of isoschizandrin.