A. D. Settimo, M. Saettone
1965
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron
Abstract
Abstract The nitration of 1-methylindole-3-aldehyde, 2-methylindole-3-aldehyde and 1,2-dimethylindole-3-aldehyde in sulphuric acid gives in ca. 92% yield mixtures of the corresponding 5- and 6-nitro derivatives. These mixtures contain a small excess of the 5-nitro derivatives. The occurrence of various side-reactions, which complicated the course of the nitration when acetic acid was used as solvent, was not observed in this case.