Cyrille Thominiaux, S. Rousse, D. Desmaële
May 21, 1999
Citations
0
Influential Citations
22
Citations
Journal
Tetrahedron-asymmetry
Abstract
Abstract Addition of 2-nitropropene to the chiral imine derived from 2-methylcyclopentanone and (S)-1-phenylethylamine furnished the expected Michael adduct. The latter compound was then efficiently converted into (R)-pentalenone through a Nef reaction. Condensation of the enamino ester derived from 2-carbethoxycyclopentanone and (S)-1-phenylethylamine with 1-nitropropene gave with excellent diastereo- and enantioselectivity the corresponding Michael adduct.