H. Rao, K. Vasantham
Jul 27, 2009
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0
Influential Citations
12
Citations
Journal
The Journal of organic chemistry
Abstract
An effective synthesis of highly functionalized 3-nitrothiophenes was achieved from the reaction of simple, inexpensive, and readily available dipotassium 2-nitro-1,1-ethylyenedithiolate with alpha-chloromethyl ketones in toluene catalyzed by tetrabutylammonium bromide (TBAB). Thiophene formation is highly sensitive and selective for chlorine, present as a leaving group in alpha-chloromethyl ketones.