K. Krohn, S. Kouam, Stephan Cludius-Brandt
Jul 1, 2008
Citations
1
Influential Citations
50
Citations
Journal
European Journal of Organic Chemistry
Abstract
Four natural nitro metabolites, 1-hydroxy-5-methoxy-2-nitronaphthalene (2), 1,5-dimethoxy-4-nitronaphthalene (3), 1-hydroxy-5-methoxy-2,4-dinitronaphthalene (4), and 1,5-dimethoxy-4,8-dinitronaphthalene (5), known from chemical synthesis but new as natural products, were isolated together with two known compounds, 1-hydroxy-5-methoxynaphthalene (1) and ergosterol (6) from an endophytic fungus, Coniothyrium sp. The structures of 1–6 were determined by spectroscopic methods including 1D and 2D NMR experiments and by mass spectrometric measurements. The structures of 1–4 were confirmed by chemical synthesis. The nitronaphthols showed considerable antibacterial, antifungal, and antialgal properties.(© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2008)