S. Loudwig, M. Goeldner
Nov 5, 2001
Citations
0
Influential Citations
18
Citations
Journal
Tetrahedron Letters
Abstract
N-Methyl-N-(o-nitrophenyl)carbamates represent new photoremovable alcohol protecting groups. This protecting group is easily incorporated by chemical coupling of the corresponding alcohol to N-methyl-N-(o-nitrophenyl)carbamoyl chloride. High yield and clean deprotection are induced by photolysis in protic solvents (water, ethanol or ethanol/water mixtures) from 254 to 365 nm.