Ahmad Rohi Ghazali, S. Inayat-Hussain
2014
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Influential Citations
15
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Abstract
N,N -dimethylacetamide (DMAC; CAS: 127-19-5) is a potent industrial solvent and also an intermediate for many organic reactions in the synthesis of agrochemicals, pharmaceuticals, and fine chemicals. Occupational exposures can occur through inhalation of its vapor and dermal contact. It is readily absorbed in humans after oral, dermal, or inhalation exposure. DMAC human exposure mainly causes liver toxicity but is less toxic to the environment. Recently, DMAC has been listed as a chemical known to cause reproductive toxicity.