M. Teimouri, A. Tayyebi
Mar 1, 2010
Citations
0
Influential Citations
3
Citations
Journal
Journal of Chemical Research
Abstract
N,N-dimethylformamide promoted the reaction of alkyl or arylisocyanides with barbituric acid derivatives which led to 5-[(alkyl or arylamino)methylene]barbituric acids in good yields at room temperature. The workup of reactions was very simple and the crude products were sufficiently pure to be used without further purification. This procedure provides an alternative method for the synthesis of aminomethylenebarbituric acids.