R. Bujok, A. Kwast, P. Cmoch
Jan 16, 2010
Citations
0
Influential Citations
19
Citations
Journal
Tetrahedron
Abstract
The addition of mono- and dianions of ethyl N-pivaloyl-3-aminocrotonate to substituted nitroarenes, followed by action of silylating or acylating agent, leads to 3-aminoquinoline carboxylic acid derivatives. Hydrolysis and decarboxylation of the latter, carried out efficiently under relatively mild conditions, afford 3-aminoquinolines diversely substituted in the benzo-fused ring.