M. Weidner‐Wells, Christine M. Boggs, B. Foleno
Jul 23, 2001
Citations
0
Influential Citations
12
Citations
Journal
Bioorganic & medicinal chemistry letters
Abstract
Oxazolidinone antibacterial agents, where the N-substituted piperazinyl group of eperezolid was replaced with a N-substituted piperidinyloxy moiety, were synthesized and shown to be active against a variety of resistant and susceptible Gram-positive organisms. The effect of ring size, positional isomerism, and fluorine substitution on antibacterial activity was examined.