M. Guo, Dao-hua Li, Zhaoguo Zhang
Nov 20, 2003
Citations
0
Influential Citations
42
Citations
Journal
The Journal of organic chemistry
Abstract
A general and efficient Cu(I)-catalyzed cross-coupling reaction of terminal alkynes and monooxalyl chloride for the synthesis of 2-oxo-3-butynoates and 2-oxo-3-butynoamides was developed. Readily available starting materials, the mild reaction conditions, wide functional group tolerance, and the obviation of stoichiometric organolithium or magnesium reagents combine to highlight this reaction.