E. Moher
Nov 25, 1996
Citations
0
Influential Citations
16
Citations
Journal
Tetrahedron Letters
Abstract
Abstract The first preparation of enantiomerically pure bicyclo[3.1.0]hexane-2-one-6-carboxylic acid ethyl ester ( 1 ), a valuable synthetic intermediate, is described. The synthesis features a retro-Diels-Alder reaction as a key step. Conditions which allow for a high yielding thermal conversion of 3 to 4 are described.