Hideyo Takahashi, Yoshinori Iwai, Yuko Hitomi
Jul 11, 2002
Citations
0
Influential Citations
35
Citations
Journal
Organic letters
Abstract
[reaction: see text] D-Mannono-1,4-lactone was efficiently converted into L-ribose in eight steps. A key step of this synthesis is the cyclization of a gamma-hydroxyalkoxamate under Mitsunobu conditions. It is noteworthy that the O-alkylation product was obtained in 94% yield and that none of the N-alkylation product was detected in this cyclization.