Chi Pengli, Cuiyue Xie, Jimao Lin
2013
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0
Influential Citations
1
Citations
Journal
Chinese Journal of Organic Chemistry
Abstract
In this paper, a novel synthetic method of 5-aminolevulinic acid (5-ALA) hydrochloride was described starting from cheap and easily available epichlorohydrin. The 5-aminolevulinic acid hydrochloride was obtained by Gabriel reaction, ring-opening, oxidation, substitution and hydrolysis. The results showed that the synthetic method has the advantages of materials being simply available, good overall yield, easily work-up and low cost.