S. Gasparyan, M. V. Alexanyan, G. Arutyunyan
Sep 28, 2016
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0
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Journal
Russian Journal of Organic Chemistry
Abstract
In reaction of 6-aminouracyles with ethyl oxochloroacetate ethyl 2-(6-amino-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-2-oxoacetates were obtained, which by further reaction with various amines afforded oxo(pyrimidinyl)acetamides. According to the data of biological tests, the synthesized compounds showed low antibacterial and antitumor activity.