G. Prakash, M. Mandal, G. Olah
Feb 2, 2001
Citations
0
Influential Citations
127
Citations
Quality indicators
Journal
Angewandte Chemie
Abstract
A very general reaction is presented to achieve the nucleophilic transfer of "CF3 " to chiral N-(tert-butylsulfinyl)imines in high yield and high stereoselectivity. Tetrabutylammonium difluorotriphenylsilicate (TBAT) functions as a fluoride source, and aromatic, heterocyclic, and aliphatic sulfinylimines react smoothly. The high stereoselectivity suggests that the reaction proceeds through an open transition state. TMS=trimethylsilyl.