A. Yagami, Nariumi Kawai, Nobuhiko Kosai
Mar 1, 2009
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Influential Citations
7
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Quality indicators
Journal
Contact Dermatitis
Abstract
Dimethyl sulfate (DMS) is a strong methylating agent widely used for organic syntheses (1). The toxic effects of DMS include potent eyes and skin irritation, respiratory disorders, and renal dysfunction and are classified as carcinogenic in humans (2). However, to our knowledge, there have been no previous published reports of allergic contact dermatitis due to DMS. We describe the first case of allergic contact dermatitis due to DMS in a patient who was occupationally sensitized following a severe acute irritant reaction to the substance.