A. East, W. Ollis, R. E. Wheeler
1969
Citations
0
Influential Citations
38
Citations
Journal
Journal of The Chemical Society C: Organic
Abstract
The root material of Derris robusta has yielded nine natural products whose structures have been determined mainly by physical methods in association with a few partial syntheses and degradations. Four of these have been shown to be new natural isoflavones: derrustone (II), derrubone (IIIa), robustone (VIa), and robustone methyl ether (VIb). The other five compounds are derivatives of the 3-aryl-4-hydroxycoumarin type, and include derrusnin (VIIb), robustic acid (IXa), robustic acid methyl ether (IXb), robustin (XIIa), and robustin methyl ether (XIIb). These 3-aryl-4-hydroxy(or methoxy)coumarins are variants upon the isoflavonoid theme. The pattern relating the structures of these co-occurring isoflavones and 3-aryl-4-oxycoumarins indicates that the biosyntheses of these two natural product types probably have many common features.