Zengxue Wang, W. Wan, Haizhen Jiang
Nov 1, 2007
Citations
0
Influential Citations
18
Citations
Journal
The Journal of organic chemistry
Abstract
A unique one-pot cyclization of 2-aminophenethyl alcohols with carboxylic acids in the presence of PPh3, CCl4, and NEt3 furnished the formation of N-acyl indolines in good to excellent yields. This new approach provides an efficient, scalable, low-cost, and direct access to the biologically important indolines which are further oxidizable to indoles and oxindoles.