Sedigheh Gholipour, A. Davoodnia, Mahboobeh Nakhaei-Moghaddam
2015
Citations
0
Influential Citations
2
Citations
Journal
Advanced Studies in Biology
Abstract
An efficient environmentally friendly procedure for the synthesis of biologically important 3-amino-1H-benzo[f]chromene-2-carbonitriles through the one‐pot, three‐component reaction of β‐naphthol, aromatic aldehydes, and malononitrile using p-dimethylaminopyridine (DMAP) as an effective and novel heterogeneous catalyst under thermal solvent‐free conditions is described. The catalyst is inexpensive and readily available and can be recovered conveniently and reused efficiently such that a considerable catalytic activity still could be achieved after the third run. Other advantages of this procedure are high yields, relatively short reaction times, easy work-up, and absence of any volatile and hazardous organic solvents.