Mahdieh Sadeghpour, Abolfazl Olyaei, Jamshid Lotfiyan
Feb 12, 2015
Citations
0
Influential Citations
7
Citations
Journal
Synthetic Communications
Abstract
Abstract A simple and highly efficient one-pot protocol for the synthesis of novel polysubstituted 1,2-dihydronaphtho[2,1-b] furans has been developed by three-component coupling reaction of 2-aminopyridines, naphthols, and glyoxal in the presence of guanidinium chloride as a polyfunctional organocatalyst under solvent-free conditions. The protocol avoids the use of expensive catalysts, toxic solvents, and chromatographic separation and provides a wide range of novel dihydronaphthofurans in good to excellent yields. GRAPHICAL ABSTRACT