K. Biswas, Arvind Kumar, Koushik Das Sarma
Apr 17, 2013
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Influential Citations
2
Citations
Journal
ACS combinatorial science
Abstract
A simple and efficient methodology has been developed for the synthesis of methyl 3,5-diaryl-isoxazoline-5-carboxylates in a high-throughput fashion. This was accomplished in one-pot by a sequence of three 2-component reactions steps (2·2·2-CR), whereby compounds were obtained in overall 30-66% isolated yields. The functional group diversity was established by synthesizing a 160-membered library.