Hitesh B. Jalani, Amit N. Pandya, D. Pandya
Sep 25, 2013
Citations
0
Influential Citations
11
Citations
Journal
ChemInform
Abstract
Abstract An efficient one-pot method for the synthesis of 2-aminothiazoles using simple starting materials like isothiocyanates, amidines/guanidines and various halomethylenes is reported. The synthesis of 2-aminothiazoles involves reactions such as nucleophilic addition, S-alkylation and intramolecular nucleophilic substitution in which amines departs as the leaving group.