H. Saeidian, M. Abdoli, R. Salimi
Nov 1, 2013
Citations
1
Influential Citations
37
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Journal
Comptes Rendus Chimie
Abstract
Abstract A convenient one-pot four-component reaction of aromatic aldehydes, β-keto esters and nitromethane in the presence an amine and 10 mol% CuO nanoparticles for the synthesis of highly substituted pyrroles is described. Excellent yields, easily available and less expensive catalyst and easy work-up are the key features of the present method. The NMR spectrum was coupled with quantum chemical calculations in DFT approach using the hybrid B3LYP exchange-correlation functional to confirm the structures of (1-benzyl-4-(4-chlorophenyl)-2-methyl-1H-pyrrol-3-yl)(phenyl)methanone 14 and 1-(1-benzyl-4-(4-chlorophenyl)-2-phenyl-1H-pyrrol-3-yl)ethanone 14′.