M. Rasouli, M. Mahdavi, P. Ranjbar
Dec 26, 2012
Citations
0
Influential Citations
26
Citations
Journal
Tetrahedron Letters
Abstract
Abstract This work describes a green and efficient one-pot synthesis of N -alkyl-2-(2-oxoazepan-1-yl)-2-arylacetamide derivatives via an Ugi four-center, three-component reaction of 6-aminohexanoic acid, aromatic aldehydes, and isocyanide derivatives in water under reflux conditions in the absence of a catalyst.