F. Liang, Dazhi Li, Lei Zhang
Oct 11, 2007
Citations
1
Influential Citations
33
Citations
Journal
Organic letters
Abstract
An amine-mediated ring-opening reaction of EWG-activated 2-methylene-1,3-dithioles (EWG = electron-withdrawing group) was disclosed, and a new route to highly substituted thiophenes was developed via the ring opening of 1,3-dithioles and subsequent intramolecular annulation and amine substitution. This one-pot reaction could proceed efficiently under mild conditions.