Tao Tong, Xin Wu, Erfei Li
Dec 3, 2018
Citations
0
Influential Citations
9
Citations
Journal
The Journal of organic chemistry
Abstract
A novel and efficient synthesis of 4-iminotetrahydropyrimidin-2-one derivatives was developed through a Cu(I)-catalyzed three-component tandem reaction employing propargylamines, isocyanates, and sulfonyl azides as starting materials. A wide range of polysubstituted 4-sulfonyliminotetrahydropyrimidin-2-ones, which might be useful in biological chemistry and medicinal science, were conveniently and efficiently assembled in one pot.