Li Zhi-hua
2013
Citations
0
Influential Citations
0
Citations
Journal
Fine Chemical Intermediates
Abstract
3-Ethoxy-4-n-decyloxy-anilionmethylene-malonic was prepared from 4-hydroxy-5-ethoxyaniline via condensation and etherification in an overall yield of 89.2%.The condensation was conducted in solvent-free solution and the etherification was catalyzed by 2.0%~5.0% of water,which accelerated the reaction speed and increased the conversion.Furthermore,it avoided using the expensive catalyst such as NaI and KI.This novel synthesis route was suitable for large-scale production as it resulted in a simple work-up process and less usage of organic solvent.