M. Billamboz, Claire Imbs, Estelle Banaszak-Leonard
Jun 5, 2017
Citations
0
Influential Citations
2
Citations
Journal
Organic Process Research & Development
Abstract
We report herein a green and scalable one-pot, three-step, pinacol-coupling–rearrangement–reduction cascade reaction useful for the formation of 2,2-diphenylethanol derivatives. The reaction is carried out in water in the presence of a commercially available and regenerable supported acid under moderate pressure. A dozen of aromatic aldehydes have been successfully submitted to the standard protocol giving the target 2,2-diarylethanol derivatives in good yield (70–85%).