Jinhua J. Song, Zhulin Tan, J. Reeves
Jul 8, 2009
Citations
0
Influential Citations
5
Citations
Journal
Tetrahedron Letters
Abstract
Treatment of unprotected 5-amino-4-methylpyrimidine (2) with n-BuLi gave dianion 3. Direct condensation of the dianion with various carboxylic acid derivatives furnished a range of 2-substituted-4,6-diazaindoles in good yields in one step without the need for protecting groups or oxidation-state adjustment.